Fueling Innovation in the Heart of Appalachia

A regional accelerator built to scale startups in biomanufacturing, medtech, advanced manufacturing, entertainment tech, and beyond.

An Unprecedented Regional Collaboration

We believe rural regions can lead the way in solving global challenges. Accelerate Appalachia connects visionary founders with the support, capital, and infrastructure they need.

Accelerate Appalachia is powered by a first-of-its-kind partnership between ETSU Research Corporation, Sync Space, and Ballad Health — leveraging the full force of the region’s entrepreneurial ecosystem. With support from Launch Tennessee and East Tennessee State University as well as leading local organizations, we’re building the next generation of scalable, innovation-driven startups.

Where Rural Ingenuity Meets Global Innovation

ß-Tech Accelerator

The ß-Tech Accelerator supports early-stage startups with mentorship, funding access, and specialized facilities—helping you grow and scale.

Intellectual Property Commercialization

Accelerate Appalachia and ETSU Research Corporation are building a robust IP Commercialization program to identify, protect, and launch innovations.

MicroVenture Fund

Aligned with Tennessee’s FundTN programs, the fund backs innovative, scalable ventures with strong regional impact potential.

Founder Support

Our mentor network connects startups with experienced industry mentors, tapping into local talent to help innovative companies grow and thrive in the region.

Driving Growth in Sectors That Define Our Region

Biomanufacturing

Innovation at the intersection of biology and industrial production

Medical & Rural Health Care

Healthcare delivery tailored for rural populations

Advanced Manufacturing

High-tech, automated manufacturing processes

Med Tech

Innovation in healthcare technology

Logistics & Supply Chain Innovation

Smart movement of goods and streamlined supply chains

Entertainment Tech

The fusion of media, music, and immersive tech experiences

Choose the accelerator program
that suits your needs

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